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TIM-1 Monoclonal Antibody (12B1C8H3), Invitrogen™

Mouse Monoclonal Antibody

235.00 € - 410.00 €

Spezifikation

Antigen TIM-1
Klon 12B1C8H3
Konzentration 1 mg/mL
Anwendungen ELISA
Klassifikation Monoclonal
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
17719743
Unterlagen ansehen Aktionsdetails
Invitrogen
MA543383
50 μL
235.00 €
50 Mikroliter
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17799563
Unterlagen ansehen Aktionsdetails
Invitrogen
MA543014
100 μL
410.00 €
100 Mikroliter
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Beschreibung

Beschreibung

Specificity: Human HAVCR1/TIM1/KIM1

CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail. The endogenous ligand for CD365 is Tim-4. In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus. The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes. Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity. CD365 has also been implicated in the T cell co-stimulation. CD365 is primarily expressed in epithelial cells. It is also highly expressed in A549, 769-P and Caco-2 and cell lines. CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.
Spezifikation

Spezifikation

TIM-1
1 mg/mL
Monoclonal
Liquid
RUO
PBS with no preservative
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1
Havcr1
IgG1
Protein A
Antibody
12B1C8H3
ELISA
Unconjugated
Mouse
Human
Q96D42
26762
Recombinant Human HAVCR1 protein.
Primary
-20° C, Avoid Freeze/Thaw Cycles
Havcr1
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Produktzertifizierungen