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ACROBiosystems Biotinylated Human 2B4 / CD244 / SLAMF4 Protein, Fc, Avitag™
Biotinylated Protein
Marke: ACROBiosystems 2B4-H82F0-25UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 50.7 kDa. As a result of glycosylation, the protein migrates as 65-80 kDa under reducing (R) condition, and 130-160 kDa under nSpezifikation
NP_057466.1 | |
25 μg | |
Cys 22 - Arg 221 | |
CD244,2B4,SLAMF4,NKR2B4,NAIL,h2B4 | |
Precision Avi | |
Fc Tag and Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
50.7 kDa | |
Biotinylated Human 2B4, Fc,Avitag (2B4-H82F0) is expressed from human 293 cells (HEK293). It contains AA Cys 22 - Arg 221 (Accession # NP_057466.1). | |
-20°C | |
2B4 | |
Human | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |