Learn More
ACROBiosystems Human CD27 / TNFRSF7 Protein, Fc Tag
HPLC-verified
Marke: ACROBiosystems CD7-H5254-200UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.9 kDa. The protein migrates as 53-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_001233 | |
200 μg | |
Thr 21 - Ile 192 | |
CD27,TNFRSF7,S152,T14,Tp55 | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
45.9 kDa | |
Human CD27, Fc Tag (CD7-H5254) is expressed from human 293 cells (HEK293). It contains AA Thr 21 - Ile 192 (Accession # NP_001233). | |
-20°C | |
CD27 | |
Human | |
50 mM Tris, 100 mM Glycine, pH7.5 | |
HEK293 | |
Immune Checkpoint Proteins |