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ACROBiosystems Rat CD47 Protein, Fc Tag

Marke:  ACROBiosystems CD7-R5256-1MG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15806297

  • 2399.32 € / 1 Milligramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.4 kDa. As a result of glycosylation, the protein migrates as 55-67 kDa under reducing (R) condition, and 100-130 kDa under non-reducing (NR) condition (SDS-P
Spezifikation

Spezifikation

40.4 kDa
Rat CD47, Fc Tag (CD7-R5256) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Lys 140 (Accession # P97829).
-20°C
CD47
Rat
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Immune Checkpoint Proteins
1 mg
Gln 19 - Lys 140
CD47,MER6,IAP,OA3
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote