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ACROBiosystems Human DNAM-1 / CD226 Protein, Fc Tag

Marke:  ACROBiosystems DN1-H5257-1MG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15806587

  • 1513.19 € / 1 Milligramm

Voraussichtliches Versanddatum: 14-10-2021

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Beschreibung

Beschreibung

DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ∼65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 52.6 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_006557
HEK293
Human
52.6 kDa
1 mg
Glu 19 - Asn 247
DNAM1,CD226,PTA1
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>95% as determined by SDS-PAGE
Human DNAM-1, Fc Tag (DN1-H5257) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Asn 247 (Accession # NP_006557).
-20°C
DNAM-1
Fc Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate