Learn More
ACROBiosystems Human Osteoactivin / GPNMB Protein, His Tag
Marke: ACROBiosystems GPB-H5229-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53.4 kDa. The protein migrates as 85-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
AAH32783 | |
100 μg | |
Ala 22 - Pro 486 | |
GPNMB,HGFIN,NMB,Osteoactivin | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
53.4 kDa | |
Human Osteoactivin, His Tag (GPB-H5229) is expressed from human 293 cells (HEK293). It contains AA Ala 22 - Pro 486 (Accession # AAH32783). | |
-20°C | |
Osteoactivin | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Bio-Markers and CD Antigens |