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ACROBiosystems Human Serpin D1 / Heparin Cofactor II Protein, His Tag

Marke:  ACROBiosystems HC2-H5224-1MG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15806927

  • 2399.32 € / 1 Milligramm
Verfügbar ab: 08-04-2024
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Beschreibung

Beschreibung

Serpin D1 is also known as Heparin cofactor 2 (HCF2), Protease inhibitor leuserpin-2 (HLS2), Heparin cofactor II (HC-II), which belongs to the serpin family. HCF2 is expressed predominantly in liver. Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, SerpinD1 / HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). In a glycosaminoglycan-independent manner, serpinD1 / HC-II also inhibits chymotrypsin. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.7 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAH35028
1 mg
Gly 20 - Ser 499
SerpinD1,HCF2,HLS2,HC-II
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
55.7 kDa
Human Serpin D1, His Tag (HC2-H5224) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - Ser 499 (Accession # AAH35028).
-20°C
Serpin D1
Human
50 mM Tris, 150 mM NaCl, pH 7.5
HEK293
Other Recombinant Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote