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ACROBiosystems Human FKBP4 / FKBP52 Protein, His,PA Tag
Brand: ACROBiosystems FK4-H52Q3-500UG
Additional Details : Netto-Gewicht : 0.00001kg
Description
Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) is also known as immunophilin FKBP52. FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP4 has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.
This protein carries a polyhistidine tag at the C-terminus, followed by a PA tag, and has a calculated MW of 55.1 kDa. The reducing (R) protein migrates as 60 kDa in SDS-PAGE.Specifications
| AAH01786 | |
| 500 μg | |
| Met 1 - Ala 459 | |
| FKBP4,FKBP52 | |
| Unconjugated | |
| His Tag and PA Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 55.1 kDa | |
| Human FKBP4, His,PA Tag (FK4-H52Q3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 459 (Accession # AAH01786). | |
| -20°C | |
| FKBP4 | |
| Human | |
| 50 mM Tris, 100 mM Glycine, pH7.5 | |
| HEK293 | |
| Other Recombinant Proteins |