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ACROBiosystems Rat GITR / TNFRSF18 Protein, His Tag
Marke: ACROBiosystems GIR-R5222-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.3 kDa. The protein migrates as 21 kDa under reducing (R) condition (SDS-PAGE).Spezifikation
| 12.3 kDa | |
| Rat GITR, His Tag (GIR-R5222) is expressed from human 293 cells (HEK293). It contains AA Gln 20 - Lys 121 (Accession # Q5M835). | |
| -20°C | |
| GITR | |
| Rat | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |
| 100 μg | |
| Gln 20 - Lys 121 | |
| AITR,GITR,TNFRSF18,CD357 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |