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ACROBiosystems Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein, His Tag&Tag Free
Marke: ACROBiosystems IT1-H52W7-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Integrin alpha 6 beta 1, also called platelet glycoprotein GPIc-IIa, is a receptor for laminin on platelets. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. ITGA6 has been shown to interact with TSPAN4 and GIPC1.
Human ITGA6&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA6 and ITGB1, has a calculated MW of 116.8 kDa (ITGA6) and 83.7 kDa (ITGB1). Subunit ITGA6 is fused with an acidic tail at the C-terminus and followed by a polyhistidSpezifikation
| NP_000201.2 (ITGA6) and NP_002202.2 (ITGB1) | |
| 100 μg | |
| Phe 24 - Gly 1012 (ITGA6) and Gln 21 - Asp 728 (ITGB1) | |
| Integrin alpha 6 beta 1,ITGA6andITGB1 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 116.8 kDa (ITGA6) and 83.7 kDa (ITGB1) | |
| Human ITGA6&ITGB1; Heterodimer Protein, His Tag&Tag; Free (IT1-H52W7) is expressed from human 293 cells (HEK293). It contains AA Phe 24 - Gly 1012 (ITGA6) and Gln 21 - Asp 728 (ITGB1) (Accession # P23229-2 (ITGA6) and P05556-1 (ITGB1)). | |
| -20°C | |
| Integrin alpha 6 beta 1 | |
| Human | |
| 50 mM Tris, 150 mM NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |