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ACROBiosystems Human EGF R Protein, Fc Tag
MALS verified
Marke: ACROBiosystems EGR-H5252-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 94.7 kDa. The protein migrates as 110-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_005219 | |
| 100 μg | |
| Leu 25 - Ser 645 | |
| EGFR,ERBB,ERBB1,HER1,PIG61,mENA | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 94.7 kDa | |
| Human EGF R, Fc Tag (EGR-H5252) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P00533-1). | |
| -20°C | |
| EGF R | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |