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ACROBiosystems Biotinylated Human B7-H4 Protein, His Tag, ultra sensitivity (primary amine labeling)
Marke: ACROBiosystems B74-H8222-25UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.4 kDa. The protein migrates as 43-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_078902 | |
25 μg | |
Phe 29 - Ala 258 | |
B7-H4,VTCN1,B7S1,B7h0.5 | |
UltraLys | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
26.4 kDa | |
MABSol™ Biotinylated Human B7-H4, His Tag, primary amine labeling (B74-H8222) is expressed from human HEK293 cells. It contains AA Phe 29 - Ala 258 (Accession # NP_078902). It is the biotinylated form of Human B7-H4, His Tag (Cat. No. B74-H5222). | |
-20°C | |
B7-H4 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |