missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Human CD30 / TNFRSF8 Protein, Fc Tag

MALS verified

Marke:  ACROBiosystems CD0-H5250-100UG

Weitere Details : Netto-Gewicht : 0.00001kg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 15836127

  • 311.92 € / 100 Mikrogramm
Verfügbar ab: 09-04-2024
Sie sich ein, um den Lagerbestand zu sehen

Bitte Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute!


Beschreibung

Beschreibung

Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 64.6 kDa. The protein migrates as 90-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_001234.2
100 μg
Phe 19 - Lys 379
TNFRSF8,CD30,D1S166E,Ki-1
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
64.6 kDa
Human CD30, Fc Tag (CD0-H5250) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2).
-20°C
CD30
Human
50 mM Tris, 100 mM Glycine, pH7.5
HEK293
Immune Checkpoint Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote