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ACROBiosystems Human GITR / TNFRSF18 Protein, Fc Tag

Marke:  ACROBiosystems GIR-H5254-100UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15836847

  • 359.89 € / 100 Mikrogramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 41.0 kDa. The protein migrates as 45-47 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_004186.1
100 μg
Gln 26 - Glu 161
AITR,GITR,TNFRSF18,CD357
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
41.0 kDa
Human GITR, Fc Tag (GIR-H5254) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Glu 161 (Accession # Q9Y5U5-1).
-20°C
GITR
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Immune Checkpoint Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote