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ACROBiosystems Human Glypican 3 / GPC3 Protein, Fc Tag, low endotoxin
low endotoxin
Marke: ACROBiosystems GP3-H5258-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
This protein carries a human IgG1 Fc tag at the C-terminus. This protein contains a furin-like convertase cleavage site, 355-RQYR-358, and will be partially processed into N and C-terminal fragment with calculated MW of 38.1 kDa and 49.3 kDa respectivelySpezifikation
| NP_004475.1 | |
| 100 μg | |
| Gln 25 - His 559 | |
| GPC3,OCI5,Glypican-3,GTR2-2,MXR7,DGSX,SDYS ,SGB,SGBS,SGBS1 | |
| Unconjugated | |
| Fc Tag | |
| Less than 0.1 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 38.1 kDa and 49.3 kDa | |
| Human Glypican 3, Fc Tag, low endotoxin (GP3-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - His 559 (Accession # P51654-1). | |
| -20°C | |
| Glypican 3 | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |