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ACROBiosystems Human DR3 / TNFRSF25 Protein, Fc Tag
Marke: ACROBiosystems TN5-H5258-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.5 kDa. The protein migrates as 53-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
AAI17190 | |
100 μg | |
Gln 25 - Gln 199 | |
TNFRSF25,DR3,APO3,DDR3,TNFRSF12,WSL,WSL1 | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
45.5 kDa | |
Human DR3, Fc Tag (TN5-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Gln 199 (Accession # AAI17190). | |
-20°C | |
DR3 / TNFRSF25 | |
Human | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
Other Recombinant Proteins |