missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Mouse LILRB4 / CD85k / ILT3 Protein, Fc Tag

Marke:  ACROBiosystems CDK-M5250-100UG

Weitere Details : Netto-Gewicht : 0.00001kg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 15846417

  • 453.96 € / 100 Mikrogramm

Voraussichtliches Versanddatum: 03-09-2021

Bitte Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute!


Beschreibung

Beschreibung

Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.7 kDa. As a result of glycosylation, the protein migrates as 60-66 kDa under reducing (R) condition, and 120-140 kDa under non-reducing (NR) condition (SDS-P
Spezifikation

Spezifikation

NP_038560.1
HEK293
Mouse
50.7 kDa
100 µg
Gly 24 - Lys 238
LILRB4,ILT3,LIR5,CD85K,HM18
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>95% as determined by SDS-PAGE
Mouse LILRB4, Fc Tag (CDK-M5250) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Lys 238 (Accession # Q64281-1).
-20°C
LILRB4
Fc Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate