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ACROBiosystems Mouse IL-17A / CTLA-8 Protein, His Tag
MALS verified
Marke: ACROBiosystems CT8-M5240-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 15.8 kDa. The protein migrates as 18 kDa, 20-23 kDa and 26 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_034682.1 | |
100 μg | |
Ala 26 - Ala 158 | |
IL-17 A,Interleukin-17 A,CTLA-8,IL-17 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |
15.8 kDa | |
Mouse IL-17 A, His Tag (CT8-M5240) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Ala 158 (Accession # Q62386-1). | |
-20°C | |
IL-17 A | |
Mouse | |
PBS, pH7.4 | |
HEK293 | |
Cytokines and Growth Factors |