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ACROBiosystems Mouse FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Twin-Strep Tag (BLI verified)
Marke: ACROBiosystems FCM-M52W2-1MG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Mouse FCGRT&B2M Heterodimer Protein, His Tag&Twin-Strep Tag (BLI verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 32.9 kDa (FCGRT) and 14.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus and subunSpezifikation
NP_034319.2 (FCGRT) and NP_033865.2 (B2M) | |
1 mg | |
Ser 22 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M) | |
FcRn,FCGRT and B2M | |
Unconjugated | |
His Tag and Strep Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
32.9 kDa (FCGRT) and 14.7 kDa (B2M) | |
Mouse FCGRT&B2M; Heterodimer Protein, His Tag&Twin-Strep; Tag (BLI verified) (FCM-M52W2) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M) (Accession # Q61559-1 (FCGRT) and P01887-1 (B2M)). | |
-20°C | |
FcRn (FCGRT and B2M) | |
Mouse | |
PBS, pH7.4 | |
HEK293 | |
MABSol™ Fc Receptors |