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ACROBiosystems Human Frizzled-2 / FZD2 (24-190) Protein, Fc Tag

Marke:  ACROBiosystems FZ2-H5255-100UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15846797

  • 419.88 € / 100 Mikrogramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

Frizzled-2 (FZD2) is also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD2 contains one FZ (frizzled) domain. FZD2 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. The Lys-Thr-X-X-X-Trp motif of FZD2 interacts with the PDZ doman of Dvl (Disheveled) family members and is involved in the activation of the Wnt/beta-catenin signaling pathway.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.4 kDa. The protein migrates as 50-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_001457.1
100 μg
Gln 24 - Pro 190
FZD2,Frizzled-2,Fz-2,hFz2,FzE2
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
44.4 kDa
Human Frizzled-2, Fc Tag (FZ2-H5255) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Pro 190 (Accession # Q14332-1).
-20°C
Frizzled-2
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Bio-Markers and CD Antigens
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote