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ACROBiosystems Human IL-17 RA / CD217 Protein, Fc Tag

MALS verified

Marke:  ACROBiosystems ILA-H5257-200UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15847077

  • N.V. / 200 Mikrogramm
Verfügbar ab: 08-04-2024
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Beschreibung

Beschreibung

Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5).

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.1 kDa. The protein migrates as 71-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_055154.3
200 μg
Leu 33 - Trp 320
CD217,CDw217,IL-17 RA,IL17R,CANDF5,hIL-17 R
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
60.1 kDa
Human IL-17 RA, Fc Tag (MALS verified) (ILA-H5257) is expressed from human 293 cells (HEK293). It contains AA Leu 33 - Trp 320 (Accession # Q96F46-1).
-20°C
IL-17 RA
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Bio-Markers and CD Antigens
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote