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ACROBiosystems Human Semaphorin 4A / SEMA4A Protein, His Tag

Marke:  ACROBiosystems SEA-H5224-100UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15847677

  • 311.92 € / 100 Mikrogramm
Verfügbar ab: 08-04-2024
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Beschreibung

Beschreibung

Semaphorin-4A (SEMA4A) is also known as Semaphorin-B (SEMAB), which belongs to the semaphorin family. SEMA4A contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one sema domain. SEMA4A is cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. SEMA4A plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. SEMA4A also promotes phosphorylation of TIMD2 and inhibits angiogenesis. SEMA4A promotes axon growth cone collapse and inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 72.7 kDa. The protein migrates as 70-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAH20974
100 μg
Gly 33 - His 683
SEMA4A,SEMAB,SEMB,Semaphorin-4 A,Semaphorin-B
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
72.7 kDa
Human Semaphorin 4 A, His Tag (SEA-H5224) is expressed from human 293 cells (HEK293). It contains AA Gly 33 - His 683 (Accession # AAH20974).
-20°C
Semaphorin 4 A
Human
PBS, pH7.4
HEK293
Other Recombinant Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote