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ACROBiosystems Human DcR3 / TNFRSF6B Protein, Fc Tag

Marke:  ACROBiosystems TNB-H5255-50UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15847847

  • 387.09 € / 50 Mikrogramm
Verfügbar ab: 03-05-2024
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Beschreibung

Beschreibung

Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.2 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAH17065
50 μg
Val 30 - His 300
TNFRSF6B,DCR3,TR6,M68
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>90% as determined by SDS-PAGE
56.2 kDa
Human DcR3, Fc Tag (TNB-H5255) is expressed from human 293 cells (HEK293). It contains AA Val 30 - His 300 (Accession # O95407-1).
-20°C
DcR3
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Other Recombinant Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote