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ACROBiosystems Biotinylated Human B7-H4 Protein, Avitag™,His Tag

Recommended for biopanning

Marke:  ACROBiosystems B74-H82E2-25UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15855967

  • 353.08 € / 25 Mikrogramm

Voraussichtliches Versanddatum: 30-08-2021

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Beschreibung

Beschreibung

V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.

This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 28 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_078902
HEK293
Human
28 kDa
25 µg
Phe 29 - Ala 258
B7-H4,VTCN1,B7S1,B7h0.5
Precision Avi
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>90% as determined by SDS-PAGE
Biotinylated Human B7-H4, Avitag,His Tag (recommended for biopanning) (B74-H82E2) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Ala 258 (Accession # NP_078902).
-20°C
B7-H4
His Tag and Avi Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
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