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ACROBiosystems Mouse CCL6 / C10 Protein, His Tag
Marke: ACROBiosystems CC6-M5222-20UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Chemokine (C-C motif) ligand 6 (CCL6), a member of the CC chemokine family, was initially identified as a transcript that is induced in bone marrow cells upon stimulation with GMCSF. CCL6 has only been identified in rodents, A human homologue for mouse CCL6 has not been identified. The mCCL6 cDNA encodes a 116 amino acid residue precursor protein with a hydrophobic signal peptide that is cleaved to yield a 95 amino acid residue mature protein. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, where it is strongly induced upon GMCSF (Cat. # GMF-H4214) stimulation. Mouse CCL6 expression was also shown to be strongly induced by IL-4 (Cat. # IL4-H4218) in mouse macrophages and by cytokine IL13 (Cat. # IL3-H4210) in mouse lung. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.7 kDa. The protein migrates as 14 kDa under reducing (R) condition (SDS-PAGE).Spezifikation
11.7 kDa | |
Mouse CCL6, His Tag (CC6-M5222) is expressed from human 293 cells (HEK293). It contains AA Gly 22 - Ala 116 (Accession # P27784). | |
-20°C | |
CCL6 | |
Mouse | |
PBS, pH7.4 | |
HEK293 | |
Cytokines and Growth Factors |
20 µg | |
Gly 22 - Ala 116 | |
CCL6,SCYA6,C10,MRP-1 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / µg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |