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ACROBiosystems Cynomolgus / Rhesus macaque CD47 Protein, Fc Tag

Marke:  ACROBiosystems CD7-C5252-100UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15856247

  • 419.88 € / 100 Mikrogramm
Verfügbar ab: 08-04-2024
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Beschreibung

Beschreibung

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.5 kDa. As a result of glycosylation, the protein migrates as 55-66 kDa under reducing (R) condition, and 100-120 kDa under non-reducing (NR) condition (SDS-P
Spezifikation

Spezifikation

NP_001253446.1
100 μg
Gln 19 - Glu 141
CD47,MER6,IAP,OA3
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
40.5 kDa
Cynomolgus / Rhesus macaque CD47, Fc Tag (CD7-C5252) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Glu 141 (Accession # F7A802-1). In the region Gln 19 - Glu 141, the AA sequence of Cynomolgus and Rhesus macaque CD47 are homologus.
-20°C
CD47
Cynomolgus Monkey, Rhesus Macaque
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Immune Checkpoint Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote