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ACROBiosystems Biotinylated Human IL-4 R alpha / CD124 Protein, Avitag™,His Tag
Biotinylated Protein
Marke: ACROBiosystems ILR-H82E9-25UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
IL-4 R alpha is also known as IL4R, CD124, IL-4RA.This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitis, asthma, or eczema. The binding of IL-4 or IL-13 to the IL-4 receptor on the surface of macrophages results in the alternative activation of those macrophages. Interleukin-4 receptor has been shown to interact with SHC1.
This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 26.9 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_000409.1 | |
| 25 μg | |
| Met 26 - His 232 | |
| IL4R,CD124,IL4RA | |
| Precision Avi | |
| His Tag and Avi Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 26.9 kDa | |
| Biotinylated Human IL-4 R alpha, Avitag,His Tag (ILR-H82E9) is expressed from human 293 cells (HEK293). It contains AA Met 26 - His 232 (Accession # NP_000409.1). | |
| -20°C | |
| IL-4 R alpha | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |