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ACROBiosystems Human Galectin-9 / LGALS9 Protein, His Tag
Marke: ACROBiosystems LG9-H5244-1MG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 36.6 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE).Spezifikation
| BAA31542.1 | |
| 1 mg | |
| Ala 2 - Thr 323 | |
| Galectin-9,LGALS9,Ecalectin | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 36.6 kDa | |
| Human Galectin-9, His Tag (LG9-H5244) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Thr 323 (Accession # O00182-2). | |
| -20°C | |
| Galectin-9 | |
| Human | |
| 20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |