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ACROBiosystems Human LILRB3 / CD85a / ILT5 Protein, Fc Tag
Marke: ACROBiosystems CDA-H5250-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3,ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 72.8 kDa. As a result of glycosylation, the protein migrates as 90-115 kDa under reducing (R) condition, and 150 kDa under non-reducing (NR) condition (SDS-PAGESpezifikation
AAB68668 (P288R) | |
100 μg | |
Gly 24 - Glu 443 | |
LILRB3,CD85a,ILT5 | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
72.8 kDa | |
Human LILRB3, Fc Tag (CDA-H5250) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Glu 443 (Accession # AAB68668 (P288R)). | |
-20°C | |
LILRB3 | |
Human | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
Immune Checkpoint Proteins |