missing translation for 'onlineSavingsMsg'
Learn More
Learn More
ACROBiosystems Human CD3 delta Protein, His Tag
Marke: ACROBiosystems CDD-H5224-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
CD3D is also known as CD3-DELTA, T3D, and is a single-pass type I membrane protein. CD3D is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. Defects in CD3D cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T-/B+/NK+ SCID) which is a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.4 kDa. The protein migrates as 18-28 kDa under reducing (R) condition (SDS-PAGE).Spezifikation
| NP_000723.1 | |
| 100 μg | |
| Phe 22 - Ala 105 | |
| CD3D,CD3-DELTA,T3D | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 11.4 kDa | |
| Human CD3 delta, His Tag (CDD-H5224) is expressed from human 293 cells (HEK293). It contains AA Phe 22 - Ala 105 (Accession # P04234-1). | |
| -20°C | |
| CD3 delta | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |