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ACROBiosystems Human Fetuin A / FETUA Protein, His Tag
Marke: ACROBiosystems FEA-H5221-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Alpha-2-HS-glycoprotein (AHSG) is also known as Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A (FETUA), is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the cystatin family of proteases inhibitors and the fetuin class of plasma binding proteins. AHSG / Fetuin A is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuins are carrier proteins like albumin. Fetuin-A / AHSG forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus AHSG / Fetuin A is a potent inhibitor of pathological calcification. Fetuin A / FETUA promotes phagocytosis of apoptotic cells and plays a role in bone development, calcium homeostasis and insulin sensitivity. Mice deficient in Fetuin-A show systemic calcification of soft tissues.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.2 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_001613.2 | |
| 100 μg | |
| Ala 19 - Val 367 | |
| AHSG,FETUA,Fetuin A | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >98% as determined by SDS-PAGE |
| 38.2 kDa | |
| Human Fetuin A, His Tag (FEA-H5221) is expressed from human 293 cells (HEK293). It contains AA Ala 19 - Val 367 (Accession # P02765-1). | |
| -20°C | |
| Fetuin A | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Other Recombinant Proteins |