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ACROBiosystems ActiveMax™ Human IL-4 Protein, Tag Free
Marke: ACROBiosystems IL4-H4218-20UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.
This protein carries no "e;tag"e;. The protein has a calculated MW of 15.0 kDa. The protein migrates as 15 kDa and 19 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| AAH67514 | |
| 20 μg | |
| His 25 - Ser 153 | |
| IL4,BCGF1,BSF1 | |
| Unconjugated | |
| Tag Free | |
| Less than 0.1 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 15.0 kDa | |
| ActiveMax™ Human IL-4, Tag Free (IL4-H4218) is expressed from human 293 cells (HEK293). It contains AA His 25 - Ser 153 (Accession # P05112-1). | |
| -20°C | |
| IL-4 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| ActiveMax™ Cytokines |