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ACROBiosystems Human PSME3 / PA28g Protein, His Tag
Marke: ACROBiosystems PS3-H5142-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation.
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 30.3 kDa. The protein migrates as 28-33 kDa under reducing (R) condition (SDS-PAGE).Spezifikation
| NP_005780.2 | |
| 100 μg | |
| Ala 2 - Tyr 254 | |
| PSME3,PA28gamma,REG-gamma | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 30.3 kDa | |
| Human PSME3, His Tag (PS3-H5142) is expressed from E.coli cells. It contains AA Ala 2 - Tyr 254 (Accession # P61289-1). | |
| -20°C | |
| PSME3 | |
| Human | |
| 50 mM Tris, 150 mM NaCl, pH7.5 | |
| E.coli | |
| Other Recombinant Proteins |