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ACROBiosystems Human 4-1BB Ligand / TNFSF9 Protein, Fc Tag
Marke: ACROBiosystems 41L-H5257-50UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 47.5 kDa. The protein migrates as 52 kDa under reducing (R) condition (SDS-PAGE).Spezifikation
| NP_003802 | |
| 50 µg | |
| Ala 50 - Glu 254 | |
| 4-1 BB Ligand,TNFSF9,CD137L | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / µg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 47.5 kDa | |
| Human 4-1 BB Ligand, Fc Tag (41 L-H5257) is expressed from human 293 cells (HEK293). It contains AA Ala 50 - Glu 254 (Accession # NP_003802). | |
| -20°C | |
| 4-1 BB Ligand | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Immune Checkpoint Proteins |