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ACROBiosystems Cynomolgus / Rhesus macaque CD27 / TNFRSF7 Protein, Mouse IgG2a Fc Tag, low endotoxin
low endotoxin
Marke: ACROBiosystems CD7-C5259-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 46.2 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| XP_005569963.1 | |
| 100 μg | |
| Ala 20 - Arg 191 | |
| CD27,TNFRSF7,S152,T14,Tp55 | |
| Unconjugated | |
| Mouse IgG Fc Tag | |
| Less than 0.1 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 46.2 kDa | |
| Cynomolgus / Rhesus macaque CD27, Mouse IgG2a Fc Tag, low endotoxin (CD7-C5259) is expressed from human 293 cells (HEK293). It contains AA Ala 20 - Arg 191 (Accession # XP_005569963.1). In the region Ala 20 - Arg 191, the AA sequence of Cynomolgus and Rhesus macaque CD27 are homologus. | |
| -20°C | |
| CD27 | |
| Cynomolgus Monkey, Rhesus Macaque | |
| 50 mM Tris, 100 mM Glycine, pH7.5 | |
| HEK293 | |
| Immune Checkpoint Proteins |