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ACROBiosystems Human Decorin Protein, His Tag
Marke: ACROBiosystems DE1-H5223-1MG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Decorin is also known as bone proteoglycan II, PGS2, SLRR1B, DCN, DSPG2 and PG40, is a secreted chondroitin /dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta). Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD).
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.8 kDa. The protein migrates as 46-55 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.Spezifikation
| NP_001911.1 | |
| 1 mg | |
| Gly 17 - Lys 359 | |
| Decorin,DCN,CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 38.8 kDa | |
| Human Decorin, His Tag (DE1-H5223) is expressed from human 293 cells (HEK293). It contains AA Gly 17 - Lys 359 (Accession # NP_001911.1). | |
| -20°C | |
| Decorin | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Other Recombinant Proteins |