missing translation for 'onlineSavingsMsg'
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ACROBiosystems Human AIMP1 / EMAP2 / SCYE1 Protein, His Tag
Marke: ACROBiosystems EM2-H5142-100UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1) is also known as multisynthase complex auxiliary component p43 and endothelial monocyte-activating polypeptide II (EMAP-II). AIMP1 is a cytokine that may be induced by apoptosis and is also released from professional antigen-presenting cells such as dendritic cells. The release of AIMP1 renders the tumor-associated vasculature sensitive to tumor necrosis factor. Furthermore, AIMP1 binds tRNA and stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. This protein possesses inflammatory cytokine activity. Also, AIMP1 negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation.
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 35.2 kDa. The protein migrates as 36 kDa under reducing (R) condition (SDS-PAGE).Spezifikation
| AAH14051.1 | |
| 100 μg | |
| Ala 2 - Lys 312 | |
| AIMP1,EMAP2,EMAPII,HLD3,SCYE1,p43,EMAP-2,EMAP-II,AIMP-1 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 35.2 kDa | |
| Human AIMP1, His Tag (EM2-H5142) is expressed from E.coli cells. It contains AA Ala 2 - Lys 312 (Accession # Q12904-1). | |
| -20°C | |
| AIMP1 | |
| Human | |
| PBS, pH7.4 | |
| E.coli | |
| Cytokines and Growth Factors |