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ACROBiosystems Biotinylated Mouse IgG2a Fc Protein, Avitag™
Biotinylated Protein
Marke: ACROBiosystems IGA-M8210-25UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.
This protein carries an Avi tag at the C-terminus. The protein has a calculated MW of 28.2 kDa. The protein migrates as 36 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
28.2 kDa | |
Biotinylated Mouse IgG2a Fc, Avitag (IGA-M8210) is expressed from human 293 cells (HEK293). It contains AA Glu 98 - Lys 330 (Accession # P01863). | |
-20°C | |
IgG2a Fc | |
Mouse | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |
25 μg | |
Glu 98 - Lys 330 | |
IgG2A | |
Precision Avi | |
Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |