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ACROBiosystems Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag

SPR & BLI verified

Marke:  ACROBiosystems FCM-H5286-50UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15896727

  • 419.88 € / 50 Mikrogramm
Verfügbar ab: 08-04-2024
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Beschreibung

Beschreibung

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

Human FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (SPR & BLI verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 31.2 kDa (FCGRT) and 13.1 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus and s
Spezifikation

Spezifikation

NP_001129491.1 (FCGRT) and AAH32589.1 (B2M)
50 μg
Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M)
FcRn,FCGRT and B2M
Unconjugated
His Tag and Strep Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
31.2 kDa (FCGRT) and 13.1 kDa (B2M)
Human FCGRT&B2M; Heterodimer Protein, His Tag&Strep; II Tag (SPR and BLI verified) (FCM-H5286) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M) (Accession # P55899-1 (FCGRT) and P61769-1 (B2M)).
-20°C
FcRn (FCGRT and B2M)
Human
PBS, pH7.4
HEK293
MABSol™ Fc Receptors
Produktvorschläge

Produktvorschläge

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Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

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