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ACROBiosystems Porcine FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag
SPR verified
Marke: ACROBiosystems FCM-P5280-50UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Porcine FCGRT&B2M Heterodimer Protein, His Tag&Strep II Tag (SPR verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 32.3 kDa (FCGRT) and 12.8 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus and subunSpezifikation
| 32.3 kDa (FCGRT) and 12.8 kDa (B2M) | |
| Porcine FCGRT&B2M; Heterodimer Protein, His Tag&Strep; II Tag (SPR verified) (FCM-P5280) is expressed from human 293 cells (HEK293). It contains AA Asp 16 - Ser 289 (FCGRT) and Val 21 - His 118 (B2M) (Accession # Q6XAV9-1 (FCGRT) and Q07717-1 (B2M)). | |
| -20°C | |
| FcRn (FCGRT and B2M) | |
| Porcine | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Fc Receptors |
| 50 μg | |
| Asp 16 - Ser 289 (FCGRT) and Val 21 - His 118 (B2M) | |
| FcRn,FCGRT and B2M | |
| Unconjugated | |
| His Tag and Strep Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |