Learn More
ACROBiosystems Biotinylated Human IL-4 Protein, Avitag™,His Tag
Biotinylated Protein
Marke: ACROBiosystems IL4-H82E0-25UG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.
This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 17.6 kDa. As a result of glycosylation, the protein migrates as 22 kDa under reducing (R) condition, and 21 kDa under non-reduSpezifikation
AAH67514 | |
25 μg | |
His 25 - Ser 153 | |
IL4,BCGF1,BSF1 | |
Precision Avi | |
His Tag and Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
17.6 kDa | |
Biotinylated Human IL-4, Avitag,His Tag (IL4-H82E0) is expressed from human 293 cells (HEK293). It contains AA His 25 - Ser 153 (Accession # AAH67514). | |
-20°C | |
IL-4 | |
Human | |
PBS, pH7.4 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |