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ACROBiosystems Human GM-CSF R alpha Protein, Fc Tag

Marke:  ACROBiosystems GRA-H5255-100ug

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16407619

  • 359.89 € / 100 Mikrogramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.9 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_006131.2
100 μg
Glu 23 - Gly 320
GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
60.9 kDa
Human GM-CSF R alpha, Fc Tag (GRA-H5255) is expressed from human 293 cells (HEK293). It contains AA Glu 23 - Gly 320 (Accession # P15509-1).
-20°C
GM-CSF R alpha
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Other Recombinant Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote