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ACROBiosystems Biotinylated Human IL-17A / CTLA-8 Protein, His, Avitag™
Biotinylated Protein
Marke: ACROBiosystems ILA-H82Q1-200ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 17.8 kDa. The protein migrates as 19-21 kDa and 23-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_002181.1 | |
| 200 μg | |
| Gly 24 - Ala 155 | |
| IL-17 A,Interleukin-17 A,CTLA-8,IL-17 | |
| Precision Avi | |
| His Tag and Avi Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 17.8 kDa | |
| Biotinylated Human IL17A, His,Avitag (ILA-H82Q1) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Ala 155 (Accession # Q16552-1). | |
| -20°C | |
| IL-17 A | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |