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ACROBiosystems Human IL-12 R beta 1 / CD212 Protein, Fc Tag
Marke: ACROBiosystems ILB-H5255-1mg
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 83.5 kDa. The protein migrates as 90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_005526.1 | |
| 1 mg | |
| Cys 24 - Glu 540 | |
| IL-12 R beta 1,IL12RB1,CD212,IL12R,IL12RB,IL-12 RB1 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by reduced SDS-PAGE |
| 83.5 kDa | |
| Human IL-12 R beta 1, Fc Tag (ILB-H5255) is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Glu 540 (Accession # P42701-1). | |
| -20°C | |
| IL-12 R beta 1 | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |