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ACROBiosystems Human LIGHT / TNFSF14 Protein, Mouse IgG2a Fc Tag, low endotoxin
low endotoxin
Marke: ACROBiosystems LIT-H5256-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.
This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 45.1 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP 003798.2 | |
| 100 μg | |
| Asp 74 - Val 240 | |
| CD258 antigen,CD258,HVEM-L,LIGHT,LTg,TNFSF14,TR2,HVEML | |
| Unconjugated | |
| Mouse IgG Fc Tag | |
| Less than 0.1 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 45.1 kDa | |
| Human LIGHT, Mouse IgG2a Fc Tag, low endotoxin (LIT-H5256) is expressed from human 293 cells (HEK293). It contains AA Asp 74 - Val 240 (Accession # O43557-1). | |
| -20°C | |
| LIGHT | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Immune Checkpoint Proteins |