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ACROBiosystems Human Properdin Protein, His Tag

Marke:  ACROBiosystems PRN-H52H3-1mg

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16407979

  • 3083.12 € / 1 Milligramm
Verfügbar ab: 09-04-2024
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Beschreibung

Beschreibung

Properdin is also known as Complement factor P, CFP, PFC, a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin is produced by many different leukocyte subsets and circulates as cyclic oligomers of monomeric subunits. Properdin on platelet/granulocyte aggregates(PGA) formation are tightly regulated by Factor H, properdin enhances PGA formation via increased production of C5a, and that inhibition of properdin function has therapeutic potential to limit thromboinflammation in diseases characterized by increased PGA formation.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.7 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_001138724.1
1 mg
Asp 28 - Leu 469
Properdin,Complement factor P,CFP,PFC
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>90% as determined by SDS-PAGE
50.7 kDa
Human Properdin, His Tag (PRN-H52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 28 - Leu 469 (Accession # P27918-1).
-20°C
Properdin
Human
PBS, pH7.4
HEK293
Other Recombinant Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote