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ACROBiosystems Human Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free
Marke: ACROBiosystems IT1-H52Wc-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Human ITGA3&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA3 and ITGB1, has a calculated MW of 133.3 kDa (ITGA3) and 83.7 kDa (ITGB1). Subunit ITGA3 is fused with an acidic tail at the C-terminus and followed by a polyhistidSpezifikation
| NP_002195.1 (ITGA3) and NP_002202.2 (ITGB1) | |
| 100 μg | |
| Phe 33 - Glu 991 (ITGA3) and Gln 21 - Asp 728 (ITGB1) | |
| Integrin alpha 3 beta 1,ITGA3andITGB1 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 113.3 kDa (ITGA3) and 83.7 kDa (ITGB1) | |
| Human ITGA3&ITGB1; Heterodimer Protein, His Tag&Tag; Free (IT1-H52Wc) is expressed from human 293 cells (HEK293). It contains AA Phe 33 - Glu 991 (ITGA3) and Gln 21 - Asp 728 (ITGB1) (Accession # P26006-2 (ITGA3) and P05556-1 (ITGB1)). | |
| -20°C | |
| Integrin alpha 3 beta 1 | |
| Human | |
| 50 mM Tris, 150 mM NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |