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ACROBiosystems Biotinylated Bovine FcRn / FCGRT&B2M Heterodimer Protein, His, Avitag™
Biotinylated SPR verified Protein
Marke: ACROBiosystems FCN-B82W3-25ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Biotinylated Bovine FcRn Heterodimer Protein, His,Avitag (SPR verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 34.5 kDa (FCGRT) and 11.6 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus, followed bySpezifikation
NP_788830.1 (FCGRT) and NP_776318.1 (B2M) | |
25 μg | |
Ala 24 - Pro 298 (FCGRT) and Ile 21 - Leu 118 (B2M) | |
FcRn,FCGRT and B2M | |
Precision Avi | |
His Tag and Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |
34.5 kDa (FCGRT) and 11.6 kDa (B2M) | |
MABSol™ Biotinylated Bovine FcRn Heterodimer Protein, His,Avitag (SPR verified) (FCN-B82W3) is expressed from human HEK293 cells. It contains AA Ala 24 - Pro 298 (FCGRT) and Ile 21 - Leu 118 (B2M) (Accession # Q3T119-1 (FCGRT) and P01888-1 (B2M)). | |
-20°C | |
FcRn (FCGRT and B2M) | |
Bovine | |
PBS, pH7.4 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |