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ACROBiosystems Mouse IL-3 R alpha / CD123 Protein, His Tag
SPR verified
Marke: ACROBiosystems ILA-M52H4-100ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.4 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| NP_032395.1 | |
| 100 μg | |
| Ser 17- Lys 331 | |
| IL3R,IL3RA,IL-3 Ra,IL-3 R-alpha,IL3RAY,IL3RX,IL3RY,CD123 antigen,CD123,hIL3Ra,hIL-3 Ra,MGC34174,IL-3 R alpha | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 36.4 kDa | |
| Mouse IL-3 R alpha, His Tag (ILA-M52H4) is expressed from human 293 cells (HEK293). It contains AA Ser 17- Lys 331 (Accession # P26952-1). | |
| -20°C | |
| IL-3 R alpha | |
| Mouse | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |