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ACROBiosystems Biotinylated Human Siglec-10 Protein, His, Avitag™
Biotinylated Protein
Marke: ACROBiosystems SI0-H82E3-25ug
Weitere Details : Netto-Gewicht : 0.00010kg
Beschreibung
The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 61.8 kDa. The protein migrates as 65-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_149121.2 | |
25 μg | |
Met 17 - Thr 546 | |
SIGLEC10,MGC126774,PRO940,Siglec10,SLG2 | |
Precision Avi | |
His Tag and Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
61.8 kDa | |
Biotinylated Human Siglec-10, His,Avitag (SI0-H82E3) is expressed from human 293 cells (HEK293). It contains AA Met 17 - Thr 546 (Accession # Q96LC7-1). | |
-20°C | |
Siglec-10 | |
Human | |
PBS with Arginine, pH7.4 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |